ACCELERATION OF LINEAR GROWTH AFTER REPEATED DOSES OF GROWTH HORMONE-RELEASING FACTOR (GRF)
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چکیده
منابع مشابه
Characteristics of growth hormone response to the administration of growth hormone-releasing hormone (GRF) in the lamb.
Human growth hormone releasing hormone (GRF 1-44 or GRF 1-29) was administered to lambs at two different physiological stages (suckling: 5-6 week-old and weaned: 14-15 week-old) when growth hormone (GH) secretory patterns were different: suckling lambs exhibited flat basal GH profiles (5-10 ng/ml) while the weaned lambs had frequent spontaneous episodes of GH release (15-65 ng/ml). The iv injec...
متن کاملEffect of growth hormone-releasing factor (1-29)NH2 and thyrotropin-releasing factor on growth hormone release in lactating sows.
Résumé. Vingt-six truies en lactation ont reçu les traitements suivants : 1) solution saline physiologique ; 2) somatocrinine ou hGRF(1-29)NH 2(20 ¡lg.kg1) ; 3) thyréolibérine (TRF) (1 ¡lg.kg) ; 4) combinaison de GRF et de TRF (20 et 1 ¡lg.kgrespectivement). La solution saline ou les peptides ont été injectés par voie sous-cutanée, deux fois par jour, du 5e au 25e jour post-partum. Les niveaux ...
متن کاملAbnormalities of growth hormone release in response to human pancreatic growth hormone releasing factor (GRF (1-44) ) in acromegaly and hypopituitarism.
Human pancreatic growth hormone releasing factor (GRF (1-44)) is the parent molecule of several peptides recently extracted from pancreatic tumours associated with acromegaly. A study was conducted to examine its effects on the release of growth hormone in normal volunteers and in patients with hypopituitarism and acromegaly. GRF (1-44) dose dependently stimulated the release of growth hormone ...
متن کاملGrowth hormone releasing factor: comparison of two analogues and demonstration of hypothalamic defect in growth hormone release after radiotherapy.
Human pancreatic growth hormone releasing factor (hpGHRF(1-40] stimulates the release of growth hormone in normal subjects and some patients with growth hormone deficiency. A study comparing the shorter chain amidated analogue hpGHRF(1-29) with an equivalent dose of hpGHRF(1-40) in seven normal subjects showed no significant difference in growth hormone response between the two preparations. Si...
متن کاملLeptin alters the response of the growth hormone releasing factor- growth hormone--insulin-like growth factor-I axis to fasting.
Proper nutritional status is critical for maintaining growth and metabolic function, playing an intimate role in neuroendocrine regulation. Leptin, the recently identified product of the obese gene, may very well be an integral signal which regulates neuroendocrine responses in times of food deprivation. The present study examines leptin's ability to regulate hormonal synthesis and secretion wi...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1984
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-198404001-00446